Article
Development of a Multi-Antigenic SARS-CoV-2 Vaccine Using a Synthetic Poxvirus Platform
2020-07-17
Abstract excerpt
<title>Abstract</title> <p>Modified Vaccinia Ankara (MVA) is a highly attenuated poxvirus vector that is widely used to develop vaccines for infectious diseases and cancer. We developed a novel vaccine platform based on a unique three-plasmid system to efficiently generate recombinant MVA vectors from chemically synthesized DNA. In response to the ongoing global pandemic caused by SARS coronavirus-2 (SARS-CoV-2),...
Topics
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- Animal Virus Infections Studies
- Herpesvirus Infections and Treatments
- Immunotherapy and Immune Responses
- Poxvirus research and outbreaks
- SARS-CoV-2 and COVID-19 Research
- vaccines and immunoinformatics approaches
- Viral gastroenteritis research and epidemiology
- Viral Infectious Diseases and Gene Expression in Insects
Identifiers and source
- Literature Corpus work
- ea8db727-56c4-5b0e-9cd3-82adc876a6ca
- DOI
- 10.21203/rs.3.rs-40198/v1
