Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Preclinical evaluation of a candidate naked plasmid DNA vaccine against SARS-CoV-2

20 Dec 2021

Abstract excerpt

New generation plasmid DNA vaccines may be a safe, fast and simple emergency vaccine platform for preparedness against emerging viral pathogens. Applying platform optimization strategies, we tested the pre-clinical immunogenicity and protective effect of a candidate DNA plasmid vaccine specific for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The DNA vaccine induced spike-specific binding IgG and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Virus Infections Studies
Share to Immunotherapy and Immune Responses
Share to SARS-CoV-2 and COVID-19 Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34930909
DOI: 10.1038/s41541-021-00419-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Preclinical evaluation of a candidate naked plasmid DNA vaccine against SARS-CoV-2PMID 34930909Read ↗

Preclinical Study of DNA Vaccines Targeting SARS-CoV-2Semantic proximity Read ↗

Comparison of DNA vaccines with AddaS03 as an adjuvant and an mRNA vaccine against SARS-CoV-2Semantic proximity Read ↗

DNA vaccine protection against SARS-CoV-2 in rhesus macaquesSemantic proximity Read ↗

Cellular and humoral immunogenicity of a candidate DNA Vaccine Expressing SARS-CoV-2 Spike Subunit 1Semantic proximity Read ↗

Immunogenic Potential of DNA Vaccine candidate, ZyCoV-D against SARS-CoV-2 in Animal ModelsSemantic proximity Read ↗

Rapid development of a synthetic DNA vaccine for COVID-19Semantic proximity Read ↗

DNA-launched RNA replicon vaccines induce potent anti-SARS-CoV-2 immune responses in miceSemantic proximity Read ↗

The Key Role of Nucleic Acid Vaccines for One HealthSemantic proximity Read ↗

A novel DNA and protein combination COVID-19 vaccine formulation provides full protection against SARS-CoV-2 in rhesus macaquesSemantic proximity Read ↗

Development of a Synthetic Poxvirus-Based SARS-CoV-2 VaccineSemantic proximity Read ↗

Assessment of immunogenicity and protective efficacy of ZyCoV-D DNA vaccine candidates in Rhesus macaques against SARS-CoV-2 infectionSemantic proximity Read ↗

Two-Component Nanoparticle Vaccine Displaying Glycosylated Spike S1 Domain Induces Neutralizing Antibody Response against SARS-CoV-2 VariantsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.