Article

In-Silico Design of Peptides for Inhibition of HLA-A*03-KLIETYFSK Complex as a New Drug Design for Treatment of Multiples Sclerosis Disease

2021-06-22

Abstract excerpt

<title>Abstract</title> <p>Multiple sclerosis is recognized as a chronic inflammatory disease. Human leukocyte antigen (HLA) plays an important role in initiating adaptive immune responses. HLA class I is present in almost all nucleated cells and presents the cleaved endogenous peptide antigens to cytotoxic T cells. HLA-A*03 is one of the HLA class I alleles, which is reported as substantially related HLA to MS d...

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Literature Corpus work: ea81ffdd-032f-5c7b-b053-6fd0ff9ab59c
DOI: 10.21203/rs.3.rs-629231/v1

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