Article

A diet-dependent host metabolite shapes the gut microbiota to protect from autoimmunity

2023-11-03

Abstract excerpt

<h4>SUMMARY</h4> Diet can protect from autoimmune disease; however, whether diet acts via the host and/or microbiome remains unclear. Here, we use a ketogenic diet (KD) as a model to dissect these complex interactions. A KD rescued the experimental autoimmune encephalomyelitis (EAE) mouse model of multiple sclerosis in a microbiota-dependent fashion. Dietary supplementation with a single KD-dependent host metabol...

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Literature Corpus work: ea68d14b-2143-590b-b96a-7bba1f82f357
DOI: 10.1101/2023.11.02.565382

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