Article

Calorie Restriction Mimetics: Upstream-Type Compounds for Modulating Glucose Metabolism

2018-11-07

Abstract excerpt

Calorie restriction (CR) has been shown to prolong the lifespan of humans, but enforcing long-term CR is difficult. Therefore, a compound that reproduces the effect of CR without CR is needed. In this review, we summarize the current knowledge on compounds with CR mimetic (CRM) effects. More than 10 compounds have been listed as CRMs, some of which are conventionally categorized as upstream-type CRMs showing glyco...

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Literature Corpus work: ea47c242-f4c7-5505-a13f-256c997ece50
DOI: 10.20944/preprints201811.0179.v1

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