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Article

Calorie restriction as an intervention in ageing

26 Nov 2015

Abstract excerpt

Ageing causes loss of function in tissues and organs, is accompanied by a chronic inflammatory process and affects life- and healthspan. Calorie restriction (CR) is a non-genetic intervention that prevents age-associated diseases and extends longevity in most of the animal models studied so far. CR produces a pleiotropic effect and improves multiple metabolic pathways, generating benefits to the whole organism....

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PMID: 26607973
DOI: 10.1113/jp270543

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