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Trophoblast Cell Subtypes and Dysfunction in the Placenta of Individuals with Preeclampsia Revealed by Single-Cell RNA Sequencing

15 Mar 2022

Abstract excerpt

Trophoblasts, important functional cells in the placenta, play a critical role in maintaining placental function . The heterogeneity of trophoblasts has been reported, but little is known about the trophoblast subtypes and distinctive functions during preeclampsia (PE). In this study, we aimed to gain insight into the cell type-specific transcriptomic changes by performing unbiased single-cell RNA sequencing...

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Pregnancy and preeclampsia studies
Reproductive System and Pregnancy
Single-cell and spatial transcriptomics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35289305
DOI: 10.14348/molcells.2021.0211

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