Article

<i>SORBS2</i> is a genetic factor contributing to cardiac malformation of 4q deletion syndrome

2020-05-14

Abstract excerpt

Chromosome 4q deletion is one of the most frequently detected genomic imbalance events in congenital heart disease (CHD) patients. However, a portion of CHD-associated 4q deletions do not include known CHD genes. Alignment of those 4q deletions defined a minimal overlapping region including only one gene- SORBS2 . Histological analysis of Sorbs2 -/- heart revealed atrial septal hypoplasia/aplasia or double atria...

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Literature Corpus work: ea16038d-520a-5b9e-8209-cea6b3d6fa8e
DOI: 10.1101/2020.05.12.087452

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