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Article

Human Genetics of Tetralogy of Fallot and Double-Outlet Right Ventricle.

Advances in experimental medicine and biology - 1 Jan 2024

Dorn Cornelia, Perrot Andreas, Grunert Marcel, Rickert-Sperling Silke

Abstract excerpt

Tetralogy of Fallot (TOF) and double-outlet right ventricle (DORV) are conotruncal defects resulting from disturbances of the second heart field and the neural crest, which can occur as isolated malformations or as part of multiorgan syndromes. Their etiology is multifactorial and characterized by overlapping genetic causes. In this chapter, we present the different genetic alterations underlying the two...

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PMID: 38884738
DOI: 10.1007/978-3-031-44087-8_36

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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