Article

Removal of disulfide from acid stress chaperone HdeA does not wholly eliminate structure or function at low pH

2021-01-18

Abstract excerpt

HdeA is an acid-stress chaperone that operates in the periplasm of various strains of pathogenic gram-negative bacteria. Its primary function is to prevent irreversible aggregation of other periplasmic proteins when the bacteria enter the acidic environment of the stomach after contaminated food is ingested; its role is therefore to help the bacteria survive long enough to enter and infect the intestines. The mech...

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Literature Corpus work: ea0775f6-70c2-56c2-80bc-aad947ce33ae
DOI: 10.1101/2021.01.17.427034

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Removal of disulfide from acid stress chaperone HdeA does not wholly eliminate structure or function at low pHDOI 10.1101/2021.01.17.427034Read

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