Article
Characterization of Helicobacter pylori HP0231 (DsbK): role in disulfide bond formation, redox homeostasis and production of Helicobacter cystein-rich protein HcpE.
Molecular microbiology - 1 Apr 2015
Lester Jeffrey, Kichler Sari, Oickle Brandon, Fairweather Spencer, Oberc Alexander, Chahal Jaspreet, Ratnayake Dinath, Creuzenet Carole
Abstract excerpt
Helicobacter pylori is a human gastric pathogen that colonizes ∼ 50% of the world's population. It can cause gastritis, gastric or duodenal ulcers and also gastric cancer. The numerous side effects of available treatments and the emergence of antibiotic resistant strains are severe concerns that justify further research into H. pylori's pathogenic mechanisms. H. pylori produces secreted proteins that may play a...
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