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PINK1 Expression as a Prognostic Biomarker in Glioblastoma Multiforme: An Observational Multicenter Study

2026-04-05

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Introduction</h4> Glioblastoma multiforme (GBM) remains the most lethal primary brain tumor with median survival of 14-15 months. Current prognostic markers inadequately stratify patient outcomes. PINK1 (PTEN-induced putative kinase 1), a mitochondrial kinase regulating mitophagy and cellular stress responses, has emerged as a promising prognostic candidate. Our preliminary analysis of 20 G...

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Literature Corpus work
ea00b913-079d-5678-ba73-5dc98972eda4
DOI
10.64898/2026.04.03.26350127
Open publication

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