Article

<i>Acanthamoeba polyphaga de novo</i> transcriptome and its dynamics during Mimivirus infection

2022-07-20

Abstract excerpt

Acanthamoeba polyphaga mimivirus (Mimivirus) is a giant virus that infects Acanthamoeba species – opportunistic human pathogens. We applied long- and short-read sequencing to generate a de novo transcriptome of the host and followed the dynamics of both host and virus transcriptomes over the course of infection. The assembled transcriptome of the host included 22,604 transcripts and 13,043 genes, with N50 = 2,3...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e9f8df3c-3cb1-501c-88e3-e8cadd9d96e1
DOI: 10.1101/2022.07.20.500700

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

<i>Acanthamoeba polyphaga de novo</i> transcriptome and its dynamics during Mimivirus infectionDOI 10.1101/2022.07.20.500700Read

Chromosome-scale assemblies of Acanthamoeba castellanii genomes provide insights into Legionella pneumophila infection-related chromatin re-organizationSemantic proximity Read

Mimiviruses: Giant viruses with novel and intriguing features (Review)Semantic proximity Read

Mimivirus shows dramatic genome reduction after intraamoebal cultureSemantic proximity Read

Comparative and systems analyses of <i>Leishmania</i> spp. non-coding RNAs through developmental stagesSemantic proximity Read

A comparative ‘omics approach to candidate pathogenicity factor discovery in the brain-eating amoeba <i>Naegleria fowleri</i>Semantic proximity Read

scRNA-seq reveals transcriptional dynamics of <i>Encephalitozoon intestinalis</i> parasites in human macrophagesSemantic proximity Read

Comparative genomic and crystal structure analyses identify a collagen glucosyltransferase from <i>Acanthamoeba Polyphaga Mimivirus</i>Semantic proximity Read

Lamarckian evolution of the giant Mimivirus in allopatric laboratory culture on amoebae.Semantic proximity Read

Mimiviridae: clusters of orthologous genes, reconstruction of gene repertoire evolution and proposed expansion of the giant virus familySemantic proximity Read

Dual Transcriptome Profiling of<i>Leishmania</i>-Infected Human Macrophages Reveals Distinct Reprogramming SignaturesSemantic proximity Read

Arp2/3 complex-mediated actin assembly drives microtubule-independent motility and phagocytosis in the evolutionarily divergent amoeba <i>Naegleria</i>Semantic proximity Read

Vaccinia-like cytoplasmic replication of the giant MimivirusSemantic proximity Read