Article

The Applications of the CRISPR/Cas9 Gene-Editing System in Treating Human Diseases

2022-08-11

Abstract excerpt

In the early 2010s, scientists realized that CRISPR/Cas9, a bacterial immune defense system against viruses that involves the CRISPR-associated protein #9 (Cas9) endonuclease enzyme, single-guide RNAs (sgRNAs), and PAM recognition, could be used to intentionally manipulate genes, essentially changing gene expression and regulation in such a way that would allow for a customized genome. Since then, CRISPR technolog...

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Literature Corpus work: e9f6a28e-59fc-525e-93a4-39201722c1ba
DOI: 10.22541/au.166023612.27704269/v1

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