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CRISPR Technology in Disease Management: An Updated Review of Clinical Translation and Therapeutic Potential.

Cell proliferation - 1 Nov 2025

Far Bahareh Farasati, Akbari Marziyeh, Habibi Mohammad Amin, Katavand Morteza, Nasseri Sherko

Abstract excerpt

CRISPR-Cas9 technology has rapidly advanced as a transformative genome-editing platform, facilitating precise genetic modifications and expanding therapeutic opportunities across various diseases. This review explores recent developments and clinical translations of CRISPR applications in oncology, genetic and neurological disorders, infectious diseases, immunotherapy, diagnostics, and epigenome editing. CRISPR...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40685330
DOI: 10.1111/cpr.70099
PMCID: PMC12584872

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