Back to search

Article

Effect of Deoxyribonuclease I Therapy on Free Circulating DNA Level and Gene Methylation Profile Changes in Patients with Endometriosis: Preliminary Data

2025-12-15

Abstract excerpt

<h4>Background: </h4> Endometriosis is a systemic chronic disease affecting seriously various aspects of fe-male health and wellbeing. It was shown to be associated with a significant increase of free circulating DNA (fcDNA) and gene methylation profile changes. The purpose of this study was to evaluate the effect of deoxyribonuclease (DNase) I therapy on these anomalies. <h4>Methods:</h4> fcDNA extraction, quanti...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
e98ad9c6-942f-599e-9e9d-26a01c2345be
DOI
10.20944/preprints202512.1221.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Effect of Deoxyribonuclease I Therapy on Free Circulating DNA Level and Gene Methylation Profile Changes in Patients with Endometriosis: Preliminary DataDOI 10.20944/preprints202512.1221.v1
Quantification of Free Circulating DNA and Differential Methylation Profiling of Selected Genes as Novel Non-Invasive Biomarkers for Endometriosis DiagnosisSemantic proximity
DNA methylation in endometriosis (Review).Semantic proximity
Methylation patterns in cell‐free plasma DNA reflect removal of the primary tumor and drug treatment of breast cancer patientsSemantic proximity
Hypermethylation of the CpG Island Spanning From Exon II to Intron III is Associated With Steroidogenic Factor 1 Expression in Stromal Cells of EndometriosisSemantic proximity
Methylation of a Novel CpG Island of Intron I Is Associated With Steroidogenic Factor I Expression in Endometriotic Stromal CellsSemantic proximity
Promoter Hypermethylation of Progesterone Receptor Isoform B (PR-B) in EndometriosisSemantic proximity
DNA methylation of HOXA10 in eutopic and ectopic endometriumSemantic proximity
Detection of DNA copy number changes in human endometriosis by comparative genomic hybridizationSemantic proximity
An Exploratory Pilot Study of Changes in Global DNA Methylation in Patients Undergoing Major Breast Surgery Under Opioid-Based General AnesthesiaSemantic proximity
Peripheral Blood Telomere Content Is Greater in Patients With Endometriosis Than in ControlsSemantic proximity
Differential DNA Hydroxymethylation in Human Uterine Leiomyoma Cells Depending on the Phase of Menstrual Cycle and Presence of MED12 Gene Mutations.Semantic proximity
Prospective study of fetal DNA in serum and disease activity during pregnancy in women with inflammatory arthritisSemantic proximity
Select a neighboring publication to make it the new centre.