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DNA methylation of HOXA10 in eutopic and ectopic endometrium

24 Jun 2014

Abstract excerpt

STUDY QUESTION: Does the methylation status of the promoter region of the HOXA10 gene differ in eutopic and ectopic endometrium? SUMMARY ANSWER: The eutopic endometrium in women with endometriosis is significantly more methylated when compared with controls. WHAT IS KNOWN ALREADY: Expression of the HOXA10 gene, which is important for successful implantation, is reduced in women affected by endometriosis. STUDY...

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PMID: 24963168
DOI: 10.1093/humrep/deu161

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