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Article

The prokaryotic SPHINX 1.8 REP protein is tissue-specific and expressed in human germline cells

2018-07-20

Abstract excerpt

<h4>ABSTRACT</h4> Small circular DNAs of 1.8 and 2.4kb were initially discovered in highly infectious CJD and scrapie particles from mammalian brain and cultured cells. Surprisingly, these protected cytoplasmic "SPHINX" DNAs contained replication (REP) initiation sequences resembling those of Acinetobacter phage viruses. An antibody was generated against a REP peptide encoded by the SPHINX 1.8 ORF that was not pr...

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Identifiers and source

Literature Corpus work
e97d9c7c-9679-54a5-9759-27ef150a6c15
DOI
10.1101/373803
Open publication

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