Article

Natural H5N1 immunity in dairy cows is durable and cross-protective but non-sterilizing

2026-01-07

Abstract excerpt

<h4>ABSTRACT</h4> Ongoing transmission of influenza A virus (H5N1) in U.S. dairy cattle threatens both animal and human health, underscoring the need to understand the durability of host immunity against reinfection with evolving genotypes. We challenged naïve and convalescent cows, infected one year prior with H5N1 genotype B3.13, with either homologous B3.13 or heterologous D1.1 genotype virus. Homologous recha...

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Literature Corpus work: e948ba69-d980-50e0-8aa9-8e7c5b1c4fa6
DOI: 10.64898/2026.01.06.697911

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