Article

aaKomp: Alignment-free amino acid <i>k</i> -mer matching for genome completeness assessment at scale

2026-03-22

Abstract excerpt

In de novo sequencing projects, genome assembly optimization requires evaluating a number of candidate assemblies to identify optimal tool parameters. Yet, current completeness assessment tools like BUSCO and compleasm require 10-80 minutes per evaluation for gigabase-scale genomes, transforming what should be rapid iteration into time-intensive processes. These tools rely on alignment-based approaches and fixed...

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Literature Corpus work: 15c2dec6-2c63-5f2a-9adb-d8eef94b9a1e
DOI: 10.64898/2026.03.19.713078

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