Article

Neutrophils Defensively Degrade Graphene Oxide in a Lateral Dimension Dependent Manner through Two Distinct Myeloperoxidase Mediated Mechanisms

2021-05-26

Abstract excerpt

<title>Abstract</title> <p>The boosting exploitation of graphene oxide (GO) increases exposure risk to human beings. However, as the first line defender, neutrophils’ mechanism of defensive behavior towards GO invasion remains unclear. Herein, we discover that neutrophils defensively degrade GO in a lateral dimension dependent manner. The micrometer-sized GO (mGO) induces NETosis by releasing neutrophil extracell...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e903b578-195a-534c-94c5-039552755d3d
DOI: 10.21203/rs.3.rs-517060/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Neutrophils Defensively Degrade Graphene Oxide in a Lateral Dimension Dependent Manner through Two Distinct Myeloperoxidase Mediated MechanismsDOI 10.21203/rs.3.rs-517060/v1Read

Recent advance in graphene-based two-dimensional nanomaterial assembly for advanced healthSemantic proximity Read

Repolarizing Neutrophils via MnO2 Nanoparticle-Activated STING Pathway Enhances Salmonella-Mediated Tumor ImmunotherapySemantic proximity Read

Low-dose nanotherapy-mediated site-specific inhibition of neutrophil extracellular traps for immunoregulatory treatment of asthmaSemantic proximity Read

Antimicrobial Microwebs of DNA–Histone Inspired from Neutrophil Extracellular TrapsSemantic proximity Read

Aging hampers neutrophil extracellular traps (NETs) efficacySemantic proximity Read

Genetically Engineered Biomimetic Nanozymes Reprogram Immune Niches to Intercept Colitis-Carcinoma TransitionSemantic proximity Read

Marginated neutrophils in the lungs effectively compete for nanoparticles targeted to the endothelium, serving as a part of the reticuloendothelial systemSemantic proximity Read

Oligomer-Nanoparticle Release from PLA Bioplastics Catalyzed by Gut Enzymes and Its Acute Inflammatory EffectSemantic proximity Read

Nanozyme-Based Supramolecular Self-Assembly As an Artificial Host Defense System For Treatment of Bacterial Infections.Semantic proximity Read

Myeloperoxidase: Growing importance in cancer pathogenesis and potential drug targetSemantic proximity Read

The Nanomaterial-Induced Bystander Effects Reprogrammed Macrophage Immune FunctionSemantic proximity Read

Bacterial Magnetosome-Hitchhiked Quick-Frozen Neutrophils for Targeted Destruction of Pre-Metastatic Niche and Prevention of Tumor Metastasis.Semantic proximity Read