Article
Marginated neutrophils in the lungs effectively compete for nanoparticles targeted to the endothelium, serving as a part of the reticuloendothelial system
2024-06-10
Abstract excerpt
Nanomedicine has long pursued the goal of targeted delivery to specific organs and cell types but has not achieved this goal with the vast majority of targets. One rare example of success in this pursuit has been the 25+ years of studies targeting the lung endothelium using nanoparticles conjugated to antibodies against endothelial surface molecules. However, here we show that such “endothelial-targeted” nanocarri...
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Identifiers and source
- Literature Corpus work
- da691417-be6c-57e6-9e3d-2b9e2877cb2f
- DOI
- 10.1101/2024.06.07.597904