Article

Convergent molecular signatures across eating disorders and obsessive-compulsive disorder in the human brain

2024-11-28

Abstract excerpt

Eating disorders (ED) and obsessive-compulsive disorder (OCD) exhibit significant clinical and genetic overlap, yet their shared molecular mechanisms remain unclear. We conducted a transcriptomic investigation of the dorsolateral prefrontal cortex (DLPFC) and caudate from 86 controls, 57 ED, and 27 OCD cases. ED was associated with robust differentially expressed genes (DEGs): 102 DEGs the DLPFC and 222 in the cau...

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Literature Corpus work: 1692f700-86cf-5f1f-b6b0-abe7ff56abbc
DOI: 10.1101/2024.11.27.24318078

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