Article

An integrated single-cell RNA-seq map of human neuroblastoma tumors and preclinical models uncovers divergent mesenchymal-like gene expression programs

2023-04-14

Abstract excerpt

<h4>ABSTRACT</h4> Neuroblastoma is a common pediatric cancer, where preclinical studies suggest that a mesenchymal-like gene expression program contributes to chemotherapy resistance. However, clinical outcomes remain poor, implying we need a better understanding of the relationship between patient tumor heterogeneity and preclinical models. Here, we generated single-cell RNA-seq maps of neuroblastoma cell lines,...

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Literature Corpus work: e8cfcbd1-b020-5aee-9071-f809959f6c47
DOI: 10.1101/2023.04.13.536639

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