Article

Targeted lung denervation in Chronic Obstructive Pulmonary Disease : pulmonary vagal denervation by radio-frequency ablation and its effects on the bronchial epithelial transcriptome

2021-01-01

Abstract excerpt

Introduction: Targeted lung denervation (TLD) is a novel bronchoscopic treatment for patients with Chronic Obstructive Pulmonary Disease (COPD). Increased parasympathetic drive causes inappropriate bronchoconstriction and mucus secretion in COPD. TLD involves the ablation of the pulmonary branches of the vagus nerve using radiofrequency energy, thereby reducing the release of neuronal acetylcholine (the principle...

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Literature Corpus work: e8b63d20-3cbd-5c69-8e38-a8737d841429
DOI: 10.25560/91726

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