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Article

Efficient embryoid-based method to improve generation of optic vesicles from human induced pluripotent stem cells

2022-03-17

Abstract excerpt

Animal models have provided many insights into ocular development and disease, but they remain suboptimal for understanding human oculogenesis. Eye development requires spatiotemporal gene expression patterns and disease phenotypes can differ significantly between humans and animal models, with patient-associated mutations causing embryonic lethality reported in some animal models. The emergence of human induced p...

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Literature Corpus work
e83d9793-5a4b-52e6-9280-cb3e199edfaf
DOI
10.12688/f1000research.108829.1
Open publication

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Efficient embryoid-based method to improve generation of optic vesicles from human induced pluripotent stem cellsDOI 10.12688/f1000research.108829.1
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