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Single-cell transcriptional landscapes of Aedes aegypti midgut and fat body after a bloodmeal

25 Jun 2025

Abstract excerpt

Aedes aegypti mosquitoes transmit arboviruses that pose a growing global health threat. After a bloodmeal, mosquitoes experience complex physiological changes orchestrated by the midgut and fat body, beginning with digestion and culminating in egg production. Our study provides comprehensive midgut and fat-body cell atlases using single-cell RNA sequencing and metabolomics. Our analyses reveal highly diverse cell...

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PMID: 40570845
DOI: 10.1016/j.xgen.2025.100924

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