Article

Adaptive Response of HK-2 Cells to High Levels of COM Crystals Highlights CaSR as an Enhancer of Crystal Adhesion

2020-09-28

Abstract excerpt

<h4>Background: </h4> Calcium oxalate monohydrate (COM) is an aetiologic factor for urolithiasis. However, how Human Kidney-2 (HK-2) cells respond to a high COM has not yet been completely elucidated. <h4>Materials: </h4> and methods: A gel-based proteomics approach was applied to investigate COM-induced cellular proteomic changes. The COM-induced upregulation of calcium-sensing receptor (CaSR) in HK-2 cells was s...

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Literature Corpus work: e7b98f1c-7fe5-5d22-b557-c1a7fedcd2f0
DOI: 10.21203/rs.3.rs-76977/v1

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Adaptive Response of HK-2 Cells to High Levels of COM Crystals Highlights CaSR as an Enhancer of Crystal AdhesionDOI 10.21203/rs.3.rs-76977/v1Read

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