Article

Blood single cell immune profiling reveals the interferon-MAPK pathway mediated adaptive immune response for COVID-19

2020-03-17

Abstract excerpt

The coronavirus disease 2019 (COVID-19) outbreak is an ongoing global health emergence, but the pathogenesis remains unclear. We revealed blood cell immune response profiles using 5’ mRNA, TCR and BCR V(D)J transcriptome analysis with single-cell resolution. Data from 134,620 PBMCs and 83,387 TCR and 12,601 BCR clones was obtained, and 56 blood cell subtypes and 23 new cell marker genes were identified from 16 par...

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Literature Corpus work: e7af5742-ba5a-523f-a1ea-0c6bf87a75c8
DOI: 10.1101/2020.03.15.20033472

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