Article

Virus–Immune Signatures Reveal Distinct Clinical Phenotypes and Predict Prognosis in Patients with Kaposi's Sarcoma

2025-11-26

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Kaposi's sarcoma (KS) is a Kaposi's sarcoma-associated herpesvirus(KSHV)-driven multicentric malignancy that demonstrates significant clinical heterogeneity. Current etiology-based classifications fail to capture the underlying biological drivers, limiting prognostic accuracy and personalized management. <bold>Objective</bold> To define biology-driven phenot...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5a5abbab-3bea-5ff3-87bc-7ad785bbacde
DOI: 10.21203/rs.3.rs-8075096/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Virus–Immune Signatures Reveal Distinct Clinical Phenotypes and Predict Prognosis in Patients with Kaposi's SarcomaDOI 10.21203/rs.3.rs-8075096/v1Read

Virus-immune signatures reveal distinct clinical phenotypes and predict prognosis in patients with Kaposi's sarcoma.Semantic proximity Read

Integrative Functional Genomics Analysis of Kaposi Sarcoma CohortsSemantic proximity Read

INTEGRATIVE FUNCTIONAL GENOMICS ANALYSIS OF KAPOSI'S SARCOMA COHORTSSemantic proximity Read

Integrative functional genomics analysis of Kaposi sarcoma cohortsSemantic proximity Read

Spatial Single-Cell Atlas Reveals KSHV-Driven Broad Cellular Reprogramming, Progenitor Expansion, Immune and Vascular Remodeling in Kaposi’s SarcomaSemantic proximity Read

Comparative transcriptome analysis of endemic and epidemic Kaposi’s sarcoma (KS) lesions and the secondary role of HIV-1 in KS pathogenesisSemantic proximity Read

Kaposi sarcoma–associated herpesvirus: immunobiology, oncogenesis, and therapySemantic proximity Read

Molecular Genetics of Kaposi's Sarcoma-Associated Herpesvirus (Human Herpesvirus 8) Epidemiology and PathogenesisSemantic proximity Read

Unique Circulating microRNA Profiles in Epidemic Kaposi’s SarcomaSemantic proximity Read

In depth characterisation of the tumour microenvironment reveals HHV-8 dependent immune regulation in HIV-associated and classic Kaposi SarcomaSemantic proximity Read

Spatial and Bulk Transcriptomics Reveal Distinct Molecular Signatures in Kaposi Sarcoma with and Without other KSHV-Associated DiseasesSemantic proximity Read

Unraveling the Kaposi Sarcoma-Associated Herpesvirus (KSHV) Lifecycle: An Overview of Latency, Lytic Replication, and KSHV-Associated DiseasesSemantic proximity Read