Article
Virus-immune signatures reveal distinct clinical phenotypes and predict prognosis in patients with Kaposi's sarcoma.
Journal of translational medicine - 27 Apr 2026
Shi Jingyi, Wang Peng, Li Tingting, Ji Xiang, Mahan Yeledan, Zhang Jingzhan, Wang Yunying, Ding Yuan, Kang Xiaojing
Abstract excerpt
BACGROUND: Kaposi’s sarcoma (KS) is a Kaposi sarcoma-associated herpesvirus (KSHV)-driven multicentric malignancy characterized by substantial clinical heterogeneity. Current etiological classification systems inadequately capture the underlying biological determinants, thereby limiting prognostic precision and personalized therapeutic strategies. We aimed to establish biology-driven phenotypic classifications of...
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