Article

DRG afferents that mediate physiologic and pathologic mechanosensation from the distal colon

2022-11-28

Abstract excerpt

The properties of dorsal root ganglia (DRG) neurons that innervate the distal colon are poorly defined, hindering our understanding of their roles in normal physiology and gastrointestinal disease. Here, we report genetically defined subsets of colon innervating DRG neurons with diverse morphologic and physiologic properties. Four colon innervating DRG neuron populations are mechanosensitive and exhibit distinct f...

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Identifiers and source

Literature Corpus work: e77b6c47-5931-5b32-aa83-1dc6a084a635
DOI: 10.1101/2022.11.27.518103

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