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Are Carbonic Anhydrases Suitable Targets to Fight Protozoan Parasitic Diseases?

28 Mar 2018

Abstract excerpt

Protozoans belonging to Plasmodium, Leishmania and Trypanosoma genera provoke widespread parasitic diseases with few treatment options and many of the clinically used drugs experiencing an extensive drug resistance phenomenon. In the last several years, the metalloenzyme Carbonic Anhydrase (CA, EC 4.2.1.1) was cloned and characterized in the genome of these protozoa, with the aim to search for a new drug target...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29589529
DOI: 10.2174/0929867325666180326160121

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