Article

Transcriptional analysis identifies overlapping and tissue-distinct profiles between Kaposi sarcoma tumors of the skin and gastrointestinal tract

2022-03-19

Abstract excerpt

Kaposi sarcoma (KS), caused by Kaposi sarcoma herpesvirus (KSHV), is a multicentric tumor characterized by abnormal vasculature and proliferation of KSHV-infected spindle cells. KS commonly involves the skin but in severe cases KS can also involve the gastrointestinal tract (GI). Here, we sought to compare the cellular and KSHV gene expression signatures of skin and GI KS lesions. Skin and GI KS were compared to n...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: fbd80b79-890a-5c7c-84dd-5002b8538b50
DOI: 10.1101/2022.03.18.484923

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Transcriptional analysis identifies overlapping and tissue-distinct profiles between Kaposi sarcoma tumors of the skin and gastrointestinal tractDOI 10.1101/2022.03.18.484923Read

Transcriptional landscape of Kaposi sarcoma tumors identifies unique immunologic signatures and key determinants of angiogenesisSemantic proximity Read

Integrative Functional Genomics Analysis of Kaposi Sarcoma CohortsSemantic proximity Read

Integrative functional genomics analysis of Kaposi sarcoma cohortsSemantic proximity Read

INTEGRATIVE FUNCTIONAL GENOMICS ANALYSIS OF KAPOSI'S SARCOMA COHORTSSemantic proximity Read

Molecular Genetics of Kaposi's Sarcoma-Associated Herpesvirus (Human Herpesvirus 8) Epidemiology and PathogenesisSemantic proximity Read

Spatial and Bulk Transcriptomics Reveal Distinct Molecular Signatures in Kaposi Sarcoma with and Without other KSHV-Associated DiseasesSemantic proximity Read

Comparative transcriptome analysis of endemic and epidemic Kaposi’s sarcoma (KS) lesions and the secondary role of HIV-1 in KS pathogenesisSemantic proximity Read

RNA-Seq of Kaposi’s sarcoma reveals alterations in glucose and lipid metabolismSemantic proximity Read

Single-Cell Transcriptomic Analysis of Kaposi SarcomaSemantic proximity Read

Altered Patterns of Cellular Gene Expression in Dermal Microvascular Endothelial Cells Infected with Kaposi's Sarcoma-Associated HerpesvirusSemantic proximity Read

Unveiling the role of KSHV‐infected human mesenchymal stem cells in Kaposi's sarcoma initiationSemantic proximity Read

Single-cell RNA sequencing identifies KSHV-infected Mesenchymal stem cell subpopulations precursors of Kaposi’s SarcomaSemantic proximity Read