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Purification of germline stem cells from adult mammalian ovaries: a step closer towards control of the female biological clock?

9 Jun 2009

Abstract excerpt

For decades it was believed that a non-renewable pool of oocyte-containing follicles is established in female mammals at birth. This cornerstone of reproductive biology was challenged 5 years ago by a study reporting on the presence of mitotically-active germ cells in juvenile and adult mouse ovaries. Additional findings presented in this study and others that followed further suggested that mammals retain the...

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PMID: 19509111
DOI: 10.1093/molehr/gap036

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