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Article

Failure of the stem cell niche rather than loss of oocyte stem cells in the aging ovary

26 Jan 2010

Abstract excerpt

The possibility of postnatal oogenesis in humans and other species has become one of today's most debated topics in the fields of reproductive and developmental biology. Wilhelm Waldeyer concluded in 1870 that oocyte production ceases with birth, and for more than a century scientists have been in consensus that the number of oocytes is gradually reduced throughout adult life [1]. A contemporary understanding of...

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PMID: 20228937
DOI: 10.18632/aging.100119

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