Article

Development and Optimization of Genetic Manipulation Systems in Group I Clostridium botulinum

2024-06-05

Abstract excerpt

Clostridium botulinum causes the disease botulism, and nontoxigenic Clostridium sporogenes is closely related to group I C. botulinum. Despite its pathogenicity, C. botulinum remains poorly characterized. Genetic manipulation is critical for understanding bacterial physiology and disease. We compared the conjugal transformation efficiencies of seven strains, including group I C. botulinum (strains 62A, 7I03-H,...

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Literature Corpus work: e6cda963-261b-5647-bc35-c8993ba0a884
DOI: 10.1101/2024.06.04.597483

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