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Conjugative Botulinum Neurotoxin-Encoding Plasmids in Clostridium botulinum

11 Jun 2010

Abstract excerpt

BACKGROUND: Clostridium botulinum produces seven distinct serotypes of botulinum neurotoxins (BoNTs). The genes encoding different subtype neurotoxins of serotypes A, B, F and several dual neurotoxin-producing strains have been shown to reside on plasmids, suggesting that intra- and interspecies transfer of BoNT-encoding plasmids may occur. The objective of the present study was to determine whether these C....

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PMID: 20552020
DOI: 10.1371/journal.pone.0011087

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