An Anaerobic Pathogen Rewires Host Metabolism to Fuel Oxidative Growth in the Inflamed Gut

Abstract excerpt

To colonize their host and cause disease, enteric pathogens must deploy their virulence factors to establish distinct nutrient niches. How obligate anaerobic pathogens construct nutrient niches in the densely populated large intestine remains poorly understood. Enterotoxigenic Bacteroides fragilis (ETBF) is considered an obligate anaerobic bacterium and has been implicated in inflammation-associated diseases, inc...

Topics

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• Antibiotic Resistance in Bacteria
• Bacterial Identification and Susceptibility Testing
• Clostridium difficile and Clostridium perfringens research
• Diet and metabolism studies
• Dietary Effects on Health
• Gut microbiota and health
• Metabolism, Diabetes, and Cancer
• Probiotics and Fermented Foods

Identifiers and source

Literature Corpus work

e6c4bbee-f1b0-563e-9a34-fb1b1951167c

DOI

10.1101/2025.05.31.657111