Article

Decoding Quetiapine's Impact: Antibiotic Efflux, Cell Membrane and Cell Wall Synthesis Genes in the Mouse Fecal Resistome

2023-06-07

Abstract excerpt

<h4>Background: </h4> As the understanding of antimicrobial activity exerted by non-antibiotic pharmaceuticals continues to evolve, the implications for antimicrobial resistance (AMR) in gut bacteria have garnered significant interest. Quetiapine, a commonly prescribed second-generation antipsychotic (SGA) drug, has been implicated in this context. Our prior research has shown that quetiapine contributes to AMR in...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e68daca8-9ec3-573f-b827-2a3fc1438513
DOI: 10.21203/rs.3.rs-3015742/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Decoding Quetiapine's Impact: Antibiotic Efflux, Cell Membrane and Cell Wall Synthesis Genes in the Mouse Fecal ResistomeDOI 10.21203/rs.3.rs-3015742/v1Read

Gut resistome development in healthy twin pairs in the first year of lifeSemantic proximity Read

Host genetic and environmental factors shape the human gut resistomeSemantic proximity Read

Early-life exposure to multiple micronutrient deficiencies induces clinically-relevant antibiotic resistance in a pre-clinical murine modelSemantic proximity Read

The Atypical Antipsychotic Quetiapine Induces Multiple Antibiotic Resistance in <i>Escherichia coli</i>Semantic proximity Read

Pediatric Fecal Microbiota Harbor Diverse and Novel Antibiotic Resistance GenesSemantic proximity Read

Exploring Alterations in the Gut Resistome in Medically Treated Inflammatory Bowel Disease PatientsSemantic proximity Read

Exogenous antibiotic resistance gene contributes to intestinal inflammation by modulating the gut microbiome and inflammatory cytokine responses in mouseSemantic proximity Read

Antimicrobial resistance gene prevalence in a population of patients with advanced dementia is related to specific pathobiontsSemantic proximity Read

The Atypical Antipsychotic Quetiapine Promotes Multiple Antibiotic Resistance in Escherichia coliSemantic proximity Read

Machine learning leveraging genomes from metagenomes identifies influential antibiotic resistance genes in the infant gut microbiomeSemantic proximity Read

Gut resistome presents a unique biome signature in chronic multi-symptom illness patients and links persistent pro-inflammatory phenotype in a mouse model reversible by fecal microbiota transferSemantic proximity Read

Differential effects of antibiotic treatment with piperacillin/tazobactam or ceftriaxone on the murine gut microbiotaSemantic proximity Read