Article

Gut resistome presents a unique biome signature in chronic multi-symptom illness patients and links persistent pro-inflammatory phenotype in a mouse model reversible by fecal microbiota transfer

2021-06-22

Abstract excerpt

<title>Abstract</title> Chronic multi-symptom illness (CMI) affects a subsection of elderly and war veterans and is associated with systemic inflammation, chronic fatigue, pain and neuroinflammation. We showed previously that an altered gut microbiome-inflammation axis aids to the symptom reporting and persistence. Here, a mouse model of CMI and a group of Gulf War veterans’ with CMI showed the presence of an...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5a47367a-280a-56b9-bf6d-89e31d11f08a
DOI: 10.21203/rs.3.rs-602469/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Gut resistome presents a unique biome signature in chronic multi-symptom illness patients and links persistent pro-inflammatory phenotype in a mouse model reversible by fecal microbiota transferDOI 10.21203/rs.3.rs-602469/v1Read

Gut DNA Virome Diversity and Its Association with Host Bacteria Regulate Inflammatory Phenotype and Neuronal Immunotoxicity in Experimental Gulf War Illness.Semantic proximity Read

High-fat and low-fiber diet elevates the gut resistome: a comparative metagenomic studySemantic proximity Read

Gut microbiota from patients with COVID-19 cause alterations in mice that resemble post-COVID symptomsSemantic proximity Read

Effects of a high fat diet on gut microbiome dysbiosis in a mouse model of Gulf War IllnessSemantic proximity Read

Exploring Alterations in the Gut Resistome in Medically Treated Inflammatory Bowel Disease PatientsSemantic proximity Read

Innate immune system signaling and CD11b + CD11c + CD103 + cell migration to the brain underlie changes in mouse behavior after microbial colonizationSemantic proximity Read

Microbiome and gut as partners in the persistence of post-inflammatory visceral pain: insight into working mechanisms of faecal transplant for therapy advanceSemantic proximity Read

Exogenous antibiotic resistance gene contributes to intestinal inflammation by modulating the gut microbiome and inflammatory cytokine responses in mouseSemantic proximity Read

Akkermansia muciniphila mediates antibiotic-induced impairment of female preference in miceSemantic proximity Read

Decoding Quetiapine's Impact: Antibiotic Efflux, Cell Membrane and Cell Wall Synthesis Genes in the Mouse Fecal ResistomeSemantic proximity Read

Antibiotics promote inflammation through the translocation of native commensal colonic bacteriaSemantic proximity Read

Impact of investigational microbiota therapeutic RBX2660 on the gut microbiome and resistome revealed by a placebo-controlled clinical trialSemantic proximity Read