Article

The Atypical Antipsychotic Quetiapine Induces Multiple Antibiotic Resistance in <i>Escherichia coli</i>

2021-11-30

Abstract excerpt

<h4>ABSTRACT</h4> Atypical antipsychotic (AAP) medication is a critical tool for treating symptoms of psychiatric disorders. While AAPs primarily target dopamine (D2) and serotonin (5HT2A and 5HT1A) receptors, they also exhibit intrinsic antimicrobial activity as an off-target effect. Because AAPs are often prescribed to patients for many years, a potential risk associated with long-term AAP use is the unintended...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 147313fd-83ff-5a2b-bce7-53bc636e207b
DOI: 10.1101/2021.11.29.470511

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The Atypical Antipsychotic Quetiapine Induces Multiple Antibiotic Resistance in <i>Escherichia coli</i>DOI 10.1101/2021.11.29.470511Read

The Atypical Antipsychotic Quetiapine Promotes Multiple Antibiotic Resistance in Escherichia coliSemantic proximity Read

Decoding Quetiapine's Impact: Antibiotic Efflux, Cell Membrane and Cell Wall Synthesis Genes in the Mouse Fecal ResistomeSemantic proximity Read

Exposure to environmental level pesticides stimulates and diversifies evolution in <i>Escherichia coli</i> towards greater antibiotic resistanceSemantic proximity Read

Selective spread of mobile antibiotic resistance genes in wastewater microbiomes driven by the non-antibiotic pharmaceutical carbamazepineSemantic proximity Read

The landscape of intrinsic and evolved fluoroquinolone resistance in <i>Acinetobacter baumannii</i> includes suppression of drug-induced prophage replicationSemantic proximity Read

Antidepressants can induce mutation and enhance persistence toward multiple antibiotics.Semantic proximity Read

TCA and SSRI Antidepressants Exert Selection Pressure for Efflux-Dependent Antibiotic Resistance Mechanisms in Escherichia coliSemantic proximity Read

The Effects of Antidepressants Fluoxetine, Sertraline, and Amitriptyline on the Development of Antibiotic Resistance in Acinetobacter BaumanniiSemantic proximity Read

Novel homologs of the multiple resistance regulator marA in antibiotic-contaminated environments.Semantic proximity Read

MarR family proteins are important regulators of clinically relevant antibiotic resistanceSemantic proximity Read

Antidepressants promote the spread of extracellular antibiotic resistance genes via transformationSemantic proximity Read

Do phenothiazines possess antimicrobial and efflux inhibitory properties?Semantic proximity Read