Article
Mis-trafficking of bicarbonate transporters: implications to human diseases.
Biochemistry and cell biology = Biochimie et biologie cellulaire - 1 Apr 2011
Almomani Ensaf Y, Chu Carmen Y S, Cordat Emmanuelle
Abstract excerpt
Bicarbonate is a waste product of mitochondrial respiration and one of the main buffers in the human body. Thus, bicarbonate transporters play an essential role in maintaining acid-base balance but also during fetal development as they ensure tight regulation of cytosolic and extracellular environments. Bicarbonate transporters belong to two gene families, SLC4A and SLC26A. Proteins from these two families are...
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