Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular analysis of human solute carrier SLC26 anion transporter disease-causing mutations using 3-dimensional homology modeling.

Biochimica et biophysica acta. Biomembranes - 1 Dec 2017

Rapp Chloe, Bai Xiaoyun, Reithmeier Reinhart A F

Abstract excerpt

The availability of the first crystal structure of a bacterial member (SLC26Dg) of the solute carrier SLC26 family of anion transporters has allowed us to create 3-dimensional models of all 10 human members (SLC26A1-A11, A10 being a pseudogene) of these membrane proteins using the Phyre2 bioinformatic tool. The homology modeling predicted that the SLC26 human proteins, like the SLC26Dg template, all consist of 14...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anion Transport Proteins
Share to Chloride-Bicarbonate Antiporters

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Deinococcus

Share to Goiter, Nodular

Share to Protein Conformation, alpha-Helical

Share to Protein Conformation, beta-Strand

Share to Structural Homology, Protein

Share to Sulfate Transporters

Source

Identifiers

PMID: 28941661
DOI: 10.1016/j.bbamem.2017.09.016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular analysis of human solute carrier SLC26 anion transporter disease-causing mutations using 3-dimensional homology modeling.PMID 28941661Read ↗

The SLC26 gene family of anion transporters and channels.Semantic proximity Read ↗

The molecular principles underlying diverse functions of the SLC26 family of proteinsSemantic proximity Read ↗

Effect of SLC26 anion transporter disease-causing mutations on the stability of the homologous STAS domain of E. coli DauA (YchM).Semantic proximity Read ↗

Pathogenetics of the human SLC26 transporters.Semantic proximity Read ↗

Cloning and characterization of SLC26A6, a novel member of the solute carrier 26 gene family.Semantic proximity Read ↗

Computational biology insights into genotype-clinical phenotype-protein phenotype relationships between novel SLC26A2 variants identified in inherited skeletal dysplasias.Semantic proximity Read ↗

Polar residues in a conserved motif spanning helices 1 and 2 are functionally important in the SulP transporter family.Semantic proximity Read ↗

Substrate binding plasticity revealed by Cryo-EM structures of SLC26A2.Semantic proximity Read ↗

Computational analysis of functional single nucleotide polymorphisms associated with SLC26A4 gene.Semantic proximity Read ↗

Structure of a SLC26 anion transporter STAS domain in complex with acyl carrier protein: implications for E. coli YchM in fatty acid metabolism.Semantic proximity Read ↗

N-glycosylation and topology of the human SLC26 family of anion transport membrane proteins.Semantic proximity Read ↗

SLC26A11 is an atypical solute carrier with dual transport-channel function mediating lysosomal sulfate transportSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.