Article

Tivantinib induces mitotic death in SHH medulloblastoma cell lines.

2024-03-05

Abstract excerpt

The c-MET kinase signalling pathway is a key player in the development of the cerebellum and it has been identified as a potential therapeutic candidate for treating medulloblastoma. Here, we confirm that c-MET and its ligand HGF are highly expressed in the SHH medulloblastoma subgroup with SHH-α and SHH-β subtypes showing the highest levels of expression of both genes, respectively. HGF treatments and siRNA-media...

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Literature Corpus work: e64a78ee-1814-5773-9ab2-1f4bdfcebd61
DOI: 10.21203/rs.3.rs-3937528/v1

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