Article

Assessment of biosafety and toxicity of hydrophilic gel for implantation in experimental in vitro and in vivo models

2021-05-14

Abstract excerpt

<h4>Background: </h4> The assessment of biosafety of pharmacologically active substances is crucial for determining the feasibility of their medical use. There are controversial issues regarding the use of substances of different origins as implants. <h4>Methods:</h4> We have conducted the comprehensive studies to determine the in vivo toxicity and in vitro genotoxicity of new generation of hydrophilic gel for imp...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e63fd4da-c96e-5f0c-b9fc-64e39173a13e
DOI: 10.21203/rs.3.rs-435527/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Assessment of biosafety and toxicity of hydrophilic gel for implantation in experimental in vitro and in vivo modelsDOI 10.21203/rs.3.rs-435527/v1Read

Cytotoxic and mutagenic potential of solutions exposed to cold atmospheric plasmaSemantic proximity Read

Preclinical safety profile of plasma prepared using the INTERCEPT Blood System.Semantic proximity Read

Pharmacokinetic and toxicological aspects of potassium sorbate food additive and its constituentsSemantic proximity Read

Host Tissue Interaction, Fate, and Risks of Degradable and Nondegradable Gel FillersSemantic proximity Read

A Nonclinical Safety Evaluation of Cold Atmospheric Plasma for Medical Applications: The Role of Genotoxicity and Mutagenicity StudiesSemantic proximity Read

Recent updates ICH S5(R3) Guideline: Detection of toxicity to reproduction for human pharmaceuticalsSemantic proximity Read

A scoping review protocol on<i>in vivo</i>human plastic exposure and health impactsSemantic proximity Read

Next Generation Risk Assessment of Cosmetics to Address Disease-Related Vulnerability. A Proof of Concept for the Sunscreen OctocryleneSemantic proximity Read

Genotoxicity Assessment of Hwanglyeonhaedok-Tang: An Herbal Formula Evaluated Using the In Vivo Alkaline Comet Assay and Pig-a Gene Mutation Assay in RatsSemantic proximity Read

Microplastics: challenges of assessment in biological samples and their implication for in vitro and in vivo effectsSemantic proximity Read

Quantitative Suspension Test for the Evaluation of a Cold Sterilization System Based on Reducing Free Radicals Compared to Autoclave Sterilization CyclesSemantic proximity Read

Genotoxicity assessment of Hwanglyeonhaedok-tang: an herbal formula evaluated using the in vivo alkaline comet assay and Pig-a gene mutation assay in rats.Semantic proximity Read