Article
Preclinical safety profile of plasma prepared using the INTERCEPT Blood System.
Vox sanguinis - 1 Oct 2003
Ciaravino V, McCullough T, Cimino G, Sullivan T
Abstract excerpt
BACKGROUND AND OBJECTIVES: The newly developed INTERCEPT Blood System for plasma uses the addition of a new psoralen, amotosalen HCl (AMOTOSALEN), followed by illumination with ultraviolet A light, to inactivate viruses, bacteria, protozoa and leucocytes that may contaminate fresh-frozen plasma (FFP). Extensive toxicology studies were performed to characterize the safety of the photochemical treatment process for...
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