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The Effects of METTL3-Mediated Regulations of the Adipogenic Differentiations of Bone Marrow MSCs Targeting PI3K/AKT Pathways on the Chemo-Resistance of AML

2020-04-15

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> The adipogenic differentiations of bone marrow mesenchymal stem cells (MSCs) result in the promotion of the chemo-resistance of AML cells. When compared with bone marrow MSCs from healthy donors (HD-MSCs), it has been observed that the MSCs from AML (AML-MSCs) displayed enhanced adipogenic differentiation abilities. However, the underlying mechanism remains elus...

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Literature Corpus work
e635a855-0cba-507e-b761-767cf377bc83
DOI
10.21203/rs.3.rs-22094/v1
Open publication

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The Effects of METTL3-Mediated Regulations of the Adipogenic Differentiations of Bone Marrow MSCs Targeting PI3K/AKT Pathways on the Chemo-Resistance of AMLDOI 10.21203/rs.3.rs-22094/v1
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