Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of gene signatures and potential therapeutic targets for acquired chemotherapy resistance in gastric cancer patients

1 Apr 2021

Abstract excerpt

BACKGROUND: Gastric cancer (GC) is the most common type of gastrointestinal cancer, and has been studied extensively. However, resistance to chemotherapeutic agents has become a major problem, leading to treatment failure. This study aimed to investigate the molecular mechanisms mediating acquired resistance to cisplatin and fluorouracil (CF) combination-based chemotherapy in GC patients. METHODS: The microarray...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ferroptosis and cancer prognosis
Share to Gastric Cancer Management and Outcomes
Share to Mechanisms of cancer metastasis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34012635
DOI: 10.21037/jgo-21-81

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of gene signatures and potential therapeutic targets for acquired chemotherapy resistance in gastric cancer patientsPMID 34012635Read ↗

Chemo-resistant Gastric Cancer Associated Gene Expression Signature: Bioinformatics Analysis Based on Gene Expression OmnibusSemantic proximity Read ↗

Establishment of panapoptotic gene signatures of platinum-chemotherapy to predict the response of chemotherapeutic drug resistance in gastric cancerSemantic proximity Read ↗

Combining multi‐dimensional data to identify a key signature (gene and miRNA) of cisplatin‐resistant gastric cancerSemantic proximity Read ↗

Integrated In silico and 3D Spheroid Models Reveal Key Genes and MiRNAs Driving Cisplatin/5-FU Resistance and Metastatic Potential in Gastric CancerSemantic proximity Read ↗

Integrated analysis to find MicroRNAs and Genes Associated with Metastasis and Cisplatin and 5-Fluorouracil Resistance Gastric CancerSemantic proximity Read ↗

Long Non-Coding RNA in Gastric Cancer: Mechanisms and Clinical Implications for Drug ResistanceSemantic proximity Read ↗

Epigenetically regulated gene expression profiles decipher four molecular subtypes with prognostic and therapeutic implications in gastric cancerSemantic proximity Read ↗

Construction of molecular subtype and prognostic model for gastric cancer based on nucleus-encoded mitochondrial genes.Semantic proximity Read ↗

Identification of Key Genes as Potential Drug Targets for Gastric CancerSemantic proximity Read ↗

Gene Regulatory Network Characterization of Gastric Cancer’s Histological Subtypes: Distinctive Biological and Clinically Relevant Master RegulatorsSemantic proximity Read ↗

Alteration of gene expression and DNA methylation in drug-resistant gastric cancerSemantic proximity Read ↗

Molecular dysexpression in gastric cancer revealed by integrated analysis of transcriptome dataSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.