Article

Significance of CTNNB1 Mutation in Cellular Process, Prognosis, and Drug Selection in Gastric Cancer

2020-07-16

Abstract excerpt

<title>Abstract</title> <p>Background: Numerous studies have reported that CTNNB1 mutant is a frequently mutated gene found in gastric cancer<bold> </bold>(GC), making this a valuable biomarker for GC. However, the underling mechanism of CTNNB1 regulating GC remains unknown.Aim of the study: To identify the significance of the CTNNB1 mutation in the prognosis and drug selection of GC, evaluate important genes and...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e618ea49-a9bb-57e9-971f-d156d84ad97f
DOI: 10.21203/rs.3.rs-41508/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Significance of CTNNB1 Mutation in Cellular Process, Prognosis, and Drug Selection in Gastric CancerDOI 10.21203/rs.3.rs-41508/v1Read

Significance of CTNNB1 Mutation in Cellular Process, Prognosis, and Drug Selection in gastric cancerSemantic proximity Read

Identification of Key Genes with Prognostic Value in Gastric Cancer by Bioinformatics AnalysisSemantic proximity Read

Genetic variation of CTNNB1 gene is associated with susceptibility and prognosis of gastric cancer in a Chinese population.Semantic proximity Read

CTGF, FN1, IL-6, THBS1, and WISP1 genes and PI3K-Akt signaling pathway as prognostic and therapeutic targets in gastric cancer identified by gene network modelingSemantic proximity Read

Integrative bioinformatic characterization of driver genes and prognostic features in human gastric carcinomaSemantic proximity Read

The Relationship Between Gene Mutations and the Clinicopathological Features and Prognosis of Gastric Cancer.Semantic proximity Read

Identification of 7 key genes as biomarkers for prognosis and metastasis of gastric cancerSemantic proximity Read

Genomic and transcriptomic profiling indicates the prognosis significance of mutational signature for TMB-high subtype in Chinese patients with gastric cancer.Semantic proximity Read

Influence of Tumor Mutational Burden on Immune-infiltrating Cells in Stomach AdenocarcinomaSemantic proximity Read

Identification of potential key genes in gastric cancer using bioinformatics analysisSemantic proximity Read

GNB1, a novel diagnostic and prognostic potential biomarker of head and neck and liver hepatocellular carcinomaSemantic proximity Read

Identification of Function Genes regulating Gastric Cancer progression using Integrated Bioinformatics AnalysisSemantic proximity Read